Epoxides are versatile and important intermediates in organic synthesis. The ring-opening reaction of epoxide associated with nucleophiles in organic is very important because this reaction can provide a suitable route to obtain various types of products. Therefore, how to develop a new synthesis method to improve the performance of the epoxide ring-opening reaction is of great importance. In this article, the comparison of ring opening of epoxides in acidic and basic environments was studied. For this purpose, amines, alcohols, and phenol were used to convert epoxides into 1,2-disubstituted compounds. Among the advantages of this method compared to the reported methods, he pointed out the reduction of reaction speed, easy separation of the product from the reaction mixture, and reaction using green solvents.
Mandal, T., & Panu, K. (2024). Epoxide Ring Opening Under Mild Conditions Using Phenol, Amine, and Alcohols. Journal of Synthetic Chemistry, 3(1), 13-23. doi: 10.22034/jsc.2024.451160.1070
MLA
Tanmay Mandal; Kriti Panu. "Epoxide Ring Opening Under Mild Conditions Using Phenol, Amine, and Alcohols". Journal of Synthetic Chemistry, 3, 1, 2024, 13-23. doi: 10.22034/jsc.2024.451160.1070
HARVARD
Mandal, T., Panu, K. (2024). 'Epoxide Ring Opening Under Mild Conditions Using Phenol, Amine, and Alcohols', Journal of Synthetic Chemistry, 3(1), pp. 13-23. doi: 10.22034/jsc.2024.451160.1070
VANCOUVER
Mandal, T., Panu, K. Epoxide Ring Opening Under Mild Conditions Using Phenol, Amine, and Alcohols. Journal of Synthetic Chemistry, 2024; 3(1): 13-23. doi: 10.22034/jsc.2024.451160.1070
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