A Method for Palladium-Catalyzed Asymmetric Couplings of Bromobenzene Derivatives: Suzuki Reactions Catalyzed by Pd Fe2O4

Document Type : Original Research

Authors

1 PhD, Allameh Tabataba’i University, cognitive sciences lab

2 Department of Cognitive Neuroscience, Laboratory of Cognitive Neuroscience, Faculty of Communication, Sciences, Allameh Tabatabaei University, Tehran, Iran.

Abstract

In the synthesizing of unsymmetrical biaryl compounds, palladium is the most effective metal catalyst. The high cost of the product limits its application on a wide scale. A good approach for reducing noble metal needs is to use nanoscale particles as active catalysts. Using magnetic nanocores as a support, precious nanoparticles can be loaded on magnetic nanocores, and catalysts can be recycled and repurposed. When applied to an external magnetic field, magnetic nanoparticles have a superparamagnetic property that allows them to collect supported catalysts quickly and easily from reaction milieus. An immobilized palladium catalyst on Fe2O4 magnetic nanoparticles was synthesized in the present study. An FT-IR spectrometer, thermogravimetric analysis, X-ray diffraction, and ICP were then used to characterize the catalyst. A high level of activity was observed in the Suzuki– Miyaura cross-coupling reaction between phenylboronic acid and aryl halides when the catalyst was prepared. Several aspects of the catalyst were investigated, including activity, Pd loading, reusability, and Pd leaching. A simple external magnetic field can be used to completely recover the supported catalyst, as evidenced by the results.

Graphical Abstract

A Method for Palladium-Catalyzed Asymmetric Couplings of Bromobenzene Derivatives: Suzuki Reactions Catalyzed by Pd Fe2O4

Keywords

Journal of Synthetic Chemistry
Volume 3, Issue 1
March 2024
Pages 1-12

Files

History

  • Receive Date: 13 February 2024
  • Revise Date: 21 February 2024
  • Accept Date: 01 March 2024

Share

How to cite

Statistics