One-pot Synthesis of Highly Functionlized Oxazoles in the Presence of Heterogeneous CuFe2O4 Catalyst

Document Type : Original Research

Authors

1 Department of Organic Chemistry, Faculty of Chemistry, University of Esfahan

2 Department of Organic Chemistry, Faculty of Chemistry, University of Esfahan.

Abstract

In this paper, a sustainable method for preparing oxazoles is described using benzoin, carboxylic acids, and ammonium acetate. The process was carried out using a water solvent and a copper catalyst. With this method, aromatic acids carrying electron-donating groups react faster and produce the related products more efficiently. It was easy to extract the reaction products in this reaction by adding water to the reaction mixture and filtering it. Since the reaction products were solids, the extraction process was simple. As a result of heat treatment of coprecipitation products, CuFe2O4 nanoparticles have been prepared by reacting Cu2+ ions with Fe3+ under alkaline conditions. By using X-ray diffraction (XRD) and transmission electron microscopy (TEM), the urchin-like superstructures have been characterized in terms of morphology and microstructure. Nanoparticles of CuFe2O4 with a size distribution between 20 and 40 nm had a cubic jacobsite structure, the results show. Magnetic properties have been detected by a vibrating sample magnetometer at room temperature. This catalyst is recyclable and environmentally friendly, which is easily separated from the test environment by a magnet and can be used for 5 cycles.

Graphical Abstract

One-pot Synthesis of Highly Functionlized Oxazoles in the Presence of Heterogeneous CuFe2O4 Catalyst

Keywords