A New Simple Methodology for the Synthesis of dihydropyrano[2,3-c]pyrazoles with Fe3O4@gC3N4 as a Green Catalyst

Document Type : Original Research

Author

Frankfurt University of Applied Sciences, Department of Chemistry, Frankfurt, 60318.

Abstract

Through the domino Knoevenagel/Michael multiple reaction of a wide variety of substrates with magnetic environmentally friendly Fe3O4/g-C3N4 nanocomposites as a catalyst in ethanol as a solvent was checked out. The catalytic properties of Fe3O4/g-C3N4 nanocomposite have been evaluated in one-pot four-component synthesis of diphenyl-1,4-dihydropyrano[2,3-c]pyrazoles. With good to excellent isolation yields and quick reaction times, a variety of easily accessible aldehydes with various substituted functional groups have been transformed to pyrazoles. High activity and selectivity allowed the catalyst to be reused up to four times in a row, and an external magnetic field made it simple to remove the catalyst from the reaction mixture.

Graphical Abstract

A New Simple Methodology for the Synthesis of dihydropyrano[2,3-c]pyrazoles with Fe3O4@gC3N4 as a Green Catalyst

Keywords